Diagnosing canine lymphoma and leukaemia
This lecture discusses the approach to diagnosis and subclassification of canine lymphoproliferative disease and how to use ancillary diagnostic tests (flow cytometry, immunocytochemistry and clonality testing) effectively.
Canine lymphoma and leukaemias are a heterogenous group of diseases that have been characterised in to numerous subtypes which offer variable prognoses. Cytology is commonly used to reach a diagnosis but it is increasingly apparent that further classification can have significant impact on the approach to medical management and prognosis. This lecture will discuss the spectrum of canine lymphoproliferative diseases, techniques for sampling, use of ancillary diagnostics such as clonality testing, immunocytochemistry and flow cytometry and will highlight when and why histopathology and immunohistochemistry is needed to complete the interpretation.
- •A review of the subclassification of canine lymphoma and leukaemia
- •Hints and tips for sample submission
- •When is phenotyping indicated and what is the most appropriate ancillary test to use
- •Practical relevance of subclassification of lymphoma and leukaemia on prognosis and therapy