What's the evidence for corticosteroid use in neurological patients?
14 Nov 2024
RVC Clinical Theatre 1
Neurology
Corticosteroids are potent pharmacological agents. Depending on the dose, they have an anti-inflammatory effect, immunosuppressive effect, anti-edema effect, or cytotoxic effect versus neoplastic lymphocytes. Corticosteroids have historically been associated with neurology like a horse and carriage. They have therefore widely, almost arbitrarily, been used for a variety of neurological disorders. The questionable efficacy of corticosteroids for most neurological presentations in combination with their unfavourable side effect profile has however resulted in a dramatic decrease of corticosteroid use in veterinary neurology.
Learning Outcomes
' Become aware of the benefits and adverse effects of corticosteroids.
' Appreciate the background and changed perception of using corticosteroids for acute spinal and brain injury.
' Get an insight into the use of corticosteroids for immune-mediated neurological disorders.
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