A new generation of hemoglobin-based oxygen carrier products and how veterinary transfusion medicine has evolved
Blood transfusion remains a cornerstone of veterinary emergency care, yet is limited by blood product availability, short shelf life, unpredictable demand, and the risk of transfusion reactions. A novel hemoglobin-based oxygen carrier (HBOC) has recently been developed, derived from purified expired blood units and designed to provide a universal, room-temperature stable alternative to traditional transfusion products. This presentation will review ongoing efforts to evaluate the feasibility and tolerability of administering this HBOC in dogs with anemia. The results of these efforts will be used to inform the design of future trials aimed at evaluating clinical efficacy and potential adverse event profile, such as nephrotoxicity. If successful, this product may represent a critical innovation in veterinary transfusion medicine, reducing waste, expanding access, and improving outcomes for anemic dogs.
- Recognise the challenges and limitations of traditional blood transfusion products in veterinary medicine.
- Understand the rationale for developing hemoglobin-based oxygen carriers (HBOCs) as alternatives to traditional blood products.
- Review how to assess feasibility and tolerability of a novel HBOC in dogs with anemia.
- Identify potential safety concerns associated with HBOCs, including transfusion reactions and nephrotoxicity.
- Evaluate how pilot data will guide future trials investigating efficacy of this novel HBOC.
- Discuss the potential role of HBOCs in addressing blood shortages and advancing veterinary transfusion medicine.
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