Conference Programme 2025

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Achieving NET ZERO: How to use the ultra-low flow Humphrey ADE-circle anaesthetic breathing system

21 Nov 2025
Gallery Suite 13
Anaesthesia

The popular multi-purpose Humphrey ADE-circle anaesthetic breathing system has two modes of use as a semi-closed system (7kg or less), and a recycling absorber system (7kg up to 250 kg). In either mode, very low flows of just 300-500ml/min are required for all animals up to 50kg due to the unique function of the “Automatic Self-adjusting Exhaust Valve” that stays closed to save all “anatomical dead space” which then opens to eliminate CO2-laden alveolar gas. 

The soda lime canister has been significantly upgraded to increase its CO2 absorbing efficiency to 100% yet use 30% less soda lime.  Sevoflurane and isoflurane flows are reduced by an average of 80%, reducing costs and pollution by the same amount. Savings with sevoflurane pay for the ADE-circle system in around 6 months. 

Sevoflurane is ideal for ultra-low flow anaesthesia using just 10 ml/kg/min - being 100% more than basal O2 requirements. Unlike isoflurane, sevoflurane uptake by muscle and fat is minimal. What is inspired is expired.  The advanced upgraded ADE-circle makes recycling easy without increasing the vaporizer or flow; it’s very stable and safe.  That’s very close to Net Zero!

  • The Humphrey ADE-circle anaesthetic system combines two modes as a semi-closed system for animals 7kg or less, and a recycling system for 7-150 kg (or more).
  • The self-adjusting exhaust valve OPENS and CLOSES automatically, saving all dead-space gas, eliminating only waste alveolar gas. Minimal fresh gas flows of just 300-500 ml/min are all that’s required for all animals up to 50 kg. That’s very close to Net Zero!
  • The new unique soda lime canister has two equal low-resistance columns, with a CO2 gas mixing chamber in between, increasing efficiency to 100%..
  • Sevoflurane: Offers quicker induction and wake-up times and stable anaesthesia. It’s ideal for recycling with the ADE-circle system, using ultra-low flows of just 5-10 ml/kg/min. This cuts vapour and oxygen costs by an average of 80%, the savings paying for the system in around 6 months!
Speakers
David Humphrey, MBBS DA, Senior University Lecturer (Retired), Research in Medical and Veterinary Anaesthesia - Specialist Research Anaesthetist, Consultant to Anaequip-Vet UK
Delivered by:
Achieving NET ZERO: How to use the ultra-low flow Humphrey ADE-circle anaesthetic breathing system
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royal veterinary college university of london logo    british veterinary association logo 

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